Explore the Enzyme Ecosystem
Organizations & Support
Organizations & Support
Organizations & Support
Organizations & Support |
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Research UniversitiesStudy and engineer enzymes for use in diagnostic assays. |
Enzyme Classification & MethodsMaintain enzyme nomenclature by catalyzed reaction. |
Industry AssociationsTrade associations of enzyme makers and formulators that publish safety, labelling and regulatory guidance. |
RegulatorsGovernment agencies that authorise medicines, devices, chemicals or food ingredients and inspect the organisations that make them. |
Research and data publishersOrganisations that publish databases, registries or reference data the sector relies on. |
Research institutesNon-university research and training organisations. |
Organizations to Explore
Organizations to Explore |
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International Union of Biochemistry and Molecular BiologyMaintains enzyme names and EC classification through its nomenclature committee, in consultation with the joint IUPAC-IUBMB commission. Classification describes the reaction an enzyme catalyses; the list requires direct experimental evidence for a proposed reaction. A name or EC number does not establish an enzyme product’s purity, activity in a new process or approval for use. Geography: International nomenclature; the checked web edition is hosted at Queen Mary University of London, United Kingdom. |
Harvard UniversityStudy and engineer enzymes for use in diagnostic assays. |
Leibniz Institute DSMZStudies microbial diversity and biological functions, maintains reference biological materials and provides enzyme information through BRENDA. BRENDA links enzyme names, reactions, organisms, kinetic measurements and references. BRENDA is part of DSMZ. Values from different experiments need their source conditions; the database does not certify a commercial enzyme preparation. Geography: Braunschweig, Germany; international research users. |
SIB Swiss Institute of Bioinformatics, ENZYMEPublishes the ENZYME nomenclature database through Expasy, based mainly on IUBMB recommendations. Users can search by EC number, name, compound or comment. Some entries are preliminary and use an n in the serial part of the number. This is a reference service, not a separate authority that approves enzyme use. Geography: Switzerland; international online resource. |
EMBL-EBIPublishes biological data and enzyme research tools. The checked Mechanism and Catalytic Site Atlas distinguishes entries with a detailed reaction mechanism from entries that identify catalytic residues only. The old Enzyme Portal has been retired, as its official training page states. Do not direct readers to that portal as a current service or treat related protein sequences as new measured mechanisms. Geography: Hinxton, United Kingdom; international data services. |
Association of Manufacturers and Formulators of Enzyme ProductsRepresents the European enzyme industry and publishes material on enzyme safety, labelling, manufacturing and regulation. Its stated member-product scope covers food, feed and technical uses such as detergents and biofuels, and explicitly excludes enzymes for pharmaceutical use. Its positions represent industry interests and do not replace official authorization. Geography: Europe; Brussels, Belgium. |
American Cleaning InstituteRepresents US cleaning-product manufacturers, formulators, ingredient suppliers and related businesses. It jointly sponsored the 2025 guidance on assessing risks of enzyme-containing consumer products with A.I.S.E. The report establishes a guidance-publishing role; it does not endorse a product or guarantee that a formulation is safe. The publisher restricts copying the full report. Geography: United States; Washington, DC. |
Detergents Europe, formerly A.I.S.E.Represents the European cleaning and hygiene products industry and publishes guidance for companies using enzymes. Its history records the change from A.I.S.E. to Detergents Europe in 2026. Its enzyme resources include safe handling, training and risk-assessment guidance. Industry guidance is not approval of a particular product. Geography: Europe; Brussels, Belgium. |
Fraunhofer Institute for Interfacial Engineering and Biotechnology IGBDevelops and scales enzyme-based chemical processes, including reaction conditions, product separation and enzyme selection. Its page links laboratory work to pilot-scale work at Fraunhofer CBP in Leuna or at partners. IGB and CBP are part of Fraunhofer. Research and process-development evidence does not establish an off-the-shelf enzyme product or a guaranteed process yield. Geography: Stuttgart and Leuna, Germany; work with project partners. |
CPISupports enzyme selection, screening, reaction development and the move from laboratory work to larger-scale processes. Its biocatalysis service includes process conditions, separation and enzyme stability. CPI describes itself as an independent research and innovation organization. Research services do not establish commercial enzyme production. Geography: North East England and Scotland, United Kingdom; companies in the UK and beyond. |
US Food and Drug AdministrationEvaluates US food additive petitions and GRAS notices for enzyme preparations. Its enzyme guidance describes chemical and technological information used in that review. The checked guidance was revised in July 2010 and states that its recommendations are nonbinding. It does not cover every safety question or establish approval of every preparation with the same enzyme name. Geography: United States. |
Health CanadaAssesses food enzyme safety and permits specified uses and sources in foods sold in Canada. Its food enzyme page points readers to the List of Permitted Food Enzymes. The checked explanation dates from May 2017; the current list and the exact preparation’s conditions must be checked before making a product-specific claim. Geography: Canada. |
European Commission, DG SANTESets the EU food enzyme framework with Member States and acts on scientific assessments. EFSA’s May 2026 procedure distinguishes its safety opinion from a possible authorization by the Commission and Member States. It also says the EU enzyme list has not yet been established and national rules still apply. Do not present a positive EFSA opinion as blanket permission to sell or use an enzyme. Geography: European Union; national rules remain relevant. |
Rice UniversityEngineers enzymes for RNA detection assays. An October 2026 university account describes work on a Cas13a variant, balancing stability, sensitivity and unwanted signals. The reported test used synthetic, noninfectious HIV material. This evidence establishes diagnostic assay research, not performance in a general patient population or approval of a clinical test. Geography: Houston, Texas, United States. |
McMaster UniversityStudies catalytic DNA for tests that detect bacteria. Its January 2025 research record describes DNAzyme-linked gels that release a visible signal after a bacterial target activates cleavage. A DNAzyme is catalytic DNA, not a protein enzyme. The record reports lake-water and patient-sample experiments; those selected study samples do not establish general clinical performance or regulatory approval. Geography: Hamilton, Ontario, Canada. |
Stanford UniversityStudies CRISPR enzyme reactions and their limits in molecular diagnostic assays. The Microfluidics Laboratory lists this work under current projects and links papers on enzyme kinetics, detector sensitivity and sample preparation. The project pages have no publication date and cite work through 2023. Geography: Stanford, California, United States. |
How They Connect
How They Connect |
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Research Universities — Research Universities OutputsOutput: Research Universities Outputs. |
Enzyme Classification & Methods — Enzyme Classification & Methods OutputsOutput: Enzyme Classification & Methods Outputs. |
Products & Services
Products & Services |
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Enzyme Classification & Methods OutputsNames and classification references for science and industry. |
Research Universities OutputsResearch results and trained staff for science and industry. |